心血管药理学；呼吸药理学

1. Dong S, Wang RR, Zhang SH, Ma YX, Ma SZ, Wang F, Shen HT, Li HB, Zhang B. Glycyrrhiza Uralensis Fisch. Alleviates Paraquat-Induced Lung Injury by Repairing Mitochondrial Respiratory Chain Dysfunction. Phytother Res. 2026 Jan 30.（共同第一作者，IF=6.3）
2. Deng X, Yuan T, Qian J, Wang Q, Wang RR, Yang X, Ma L, Li M, Du G, Li M, Zeng X, Fang L, Zhao J. Rare TRAF5 coding variants in systemic lupus erythematosus patients aggravate pulmonary hypertension via endothelial dysfunction. Innovation (Camb). 2025 Sep 4;7(2):101111.（IF=25.7）
3. Zhang X, Chen M, Wang R, Liu R, Gong D, Zhang M, He Y, Du G, Fang L, Yuan T. Flavonoids: Potential New Drug Candidates for Attenuating Vascular Remodeling in Pulmonary Hypertension. Int J Mol Sci. 2025 Dec 24;27(1):210.（IF=4.9）
4. Dawuti A, Sun S, Wang R, Gong D, Liu R, Kong D, Yuan T, Zhou J, Lu Y, Wang S, Du G, Fang L. Salvianolic acid A alleviates heart failure with preserved ejection fraction via regulating TLR/Myd88/TRAF/NF-κB and p38MAPK/CREB signaling pathways. Biomed Pharmacother. 2023 Dec;168:115837.（IF=7.5）
5. Gong D, Yuan T, Wang R, Sun S, Dawuti A, Wang S, Du G, Fang L. Network pharmacology approach and experimental verification of Dan-Shen Decoction in the treatment of ischemic heart disease. Pharm Biol. 2023 Dec;61(1):69-79. （IF=4.8）
6. Sun S, Gong D, Liu R, Wang R, Chen D, Yuan T, Wang S, Xing C, Lv Y, Du G, Fang L. Puerarin Inhibits NLRP3-Caspase-1-GSDMD-Mediated Pyroptosis via P2X7 Receptor in Cardiomyocytes and Macrophages. Int J Mol Sci. 2023 Aug 24;24(17):13169.（IF=4.9）
7. Liu R, Yuan T, Wang R, Gong D, Wang S, Du G, Fang L. Insights into Endothelin Receptors in Pulmonary Hypertension. Int J Mol Sci. 2023 Jun 16;24(12):10206.（IF=4.9）
8. Gong DF, Sun SC, Wang RR, Dawuti A, Kong DW, Liu RQ, Du LD, Wang SB, Lu Y, Yuan TY, Du GH, Fang LH. Salvianolic acid A improve mitochondrial respiration and cardiac function via inhibiting apoptosis pathway through CRYAB in diabetic cardiomyopathy. Biomed Pharmacother. 2023 Apr;160:114382.（IF=7.5）
9. Sun S, Dawuti A, Gong D, Wang R, Yuan T, Wang S, Xing C, Lu Y, Du G, Fang L. Puerarin-V Improve Mitochondrial Respiration and Cardiac Function in a Rat Model of Diabetic Cardiomyopathy via Inhibiting Pyroptosis Pathway through P2X7 Receptors. Int J Mol Sci. 2022 Oct 27;23(21):13015.（IF=4.9）
10. Chen D, Zhang HF, Yuan TY, Sun SC, Wang RR, Wang SB, Fang LH, Lyu Y, Du GH. Puerarin-V prevents the progression of hypoxia- and monocrotaline-induced pulmonary hypertension in rodent models. Acta Pharmacol Sin. 2022 Sep;43(9):2325-2339.（IF=8.4）
11. Dawuti A, Sun S, Wang R, Gong D, Yuan T, Zhang L, Yang S, Xing J, Zheng R, Lu Y, Wang S, Fang L, Du G. Systems Pharmacology-Based Strategy to Investigate Pharmacological Mechanisms of Total Flavonoids in Dracocephalum moldavica on Chronic Heart Failure. Int J Mol Sci. 2022 Jul 29;23(15):8409.（IF=4.9）
12. Wang RR, Yuan TY, Wang JM, Chen YC, Zhao JL, Li MT, Fang LH, Du GH. Immunity and inflammation in pulmonary arterial hypertension: From pathophysiology mechanisms to treatment perspective. Pharmacol Res. 2022 Jun;180:106238.(IF=10.5)
13. Wang RR, Yuan TY, Chen D, Chen YC, Sun SC, Wang SB, Kong LL, Fang LH, Du GH. Dan-Shen-Yin Granules Prevent Hypoxia-Induced Pulmonary Hypertension via STAT3/HIF-1α/VEGF and FAK/AKT Signaling Pathways. Front Pharmacol. 2022 Mar 11;13:844400.(IF=4.8)
14. Xia Y, Jia C, Xue Q, Jiang J, Xie Y, Wang R, Ran Z, Xu F, Zhang Y, Ye T. Antipsychotic Drug Trifluoperazine Suppresses Colorectal Cancer by Inducing G0/G1 Arrest and Apoptosis. Front Pharmacol. 2019 Sep 13;10:1029.（IF=4.8）
15. Feng Z, Xia Y, Gao T, Xu F, Lei Q, Peng C, Yang Y, Xue Q, Hu X, Wang Q, Wang R, Ran Z, Zeng Z, Yang N, Xie Z, Yu L. The antipsychotic agent trifluoperazine hydrochloride suppresses triple-negative breast cancer tumor growth and brain metastasis by inducing G0/G1 arrest and apoptosis. Cell Death Dis. 2018 Sep 26;9(10):1006.（IF=9.6）
16. Xiao W, Ruan S, Yu W, Wang R, Hu C, Liu R, Gao H. Normalizing Tumor Vessels To Increase the Enzyme-Induced Retention and Targeting of Gold Nanoparticle for Breast Cancer Imaging and Treatment. Mol Pharm. 2017 Oct 2;14(10):3489-3498.（IF=4.5）
17. 刘芮绮,袁天翊,王冉冉,等.祖卡木颗粒对低氧性肺动脉高压的药效及机制研究[J].医药导报,2024,43(04):550-560.
18. 王建美,王冉冉,袁天翊,等.瓜蒌薤白汤预防低氧性肺动脉高压作用及其机制研究[J].中药药理与临床, 2023, 39(05): 8-15.
19. 王建美,王冉冉,袁天翊,等.达原饮通过NF-κB信号通路预防低氧性肺动脉高压作用及机制研究[J].药学学报,2023,58(04):928-937.
20. 龚迪菲,王冉冉,袁天翊,等.复方利血平氨苯蝶啶片对离体胸主动脉血管环的舒张作用及机制研究[J].药学学报,2022,57(11):3339-3344.
21. 王冉冉,方莲花,杜冠华.抗肺动脉高压药物及其作用机制研究进展[J].中国药理学通报,2020,36(07):893-897.

教学科研项目：
1. 四川省自然科学基金青年项目，基于“培土生金”理论的甘草靶向Sirt1/PGC-1α通路调控线粒体-血管重塑偶联改善低氧性肺动脉高压的机制研究，2026NSFSC1830，2026.01-2027.12，主持
2. 国家自然科学基金面上项目，Smad4调控网络在慢性血栓栓塞性肺动脉高压血管重塑中的机制及匹诺塞林干预作用研究，82073853,2019.01-2024.12，参与
3. sunbet官网引进人才启动项目，2024.09-2029.09，主持
4. sunbet官网教改项目，智慧教育视域下《人体解剖生理学》虚实融合教学模式创新与实践，2026.01-2027.12
授权专利：
1.包含蔓荆子的中药组方和提取物及其治疗肺动脉高压的用途。2025，授权公告号：CN 117815317 B
2.包含槟榔的中药组方、提取物及其预防治疗肺动脉高压的用途。2025，授权公告号：CN 118178583 B
出版专著:
《炎症性肠病的实验动物学》化学工业出版社，ISBN：9787122489579，2026年2月，编委